Comment on "High-sensitivity cardiac troponin: hype, help, and reality".

نویسندگان

  • Tobias Reichlin
  • Raphael Twerenbold
  • Christian Mueller
چکیده

1. Jaffe AS, Apple FS. High-sensitivity cardiac troponin: hype, help, and reality. Clin Chem 2010;56:342–4. 2. Keller T, Zeller T, Peetz D, Tzikas S, Roth A, Czyz E, et al. Sensitive troponin I assay in early diagnosis of acute myocardial infarction. N Engl J Med 2009;361:868–77. 3. Reichlin T, Hochholzer W, Bassetti S, Steuer S, Stelzig C, Hartwiger S, et al. Early diagnosis of myocardial infarction with sensitive cardiac troponin assays. N Engl J Med 2009;361:858–67. 4. Apple FS. A new season for cardiac troponin assays: it’s time to keep a scorecard. Clin Chem 2009;55:1303–6. 5. Wu AH, Agee SJ, Lu QA, Todd J, Jaffe AS. Specificity of a high-sensitivity cardiac troponin I assay using single-molecule-counting technology. Clin Chem 2009;55:196–8.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

High-sensitivity cardiac troponin: hype, help, and reality.

Articles in The New England Journal of Medicine get tremendous publicity, some justified and some not. Recently, 2 articles and an editorial (1–3 ) were published about the use of “high-sensitivity” cardiac troponin (cTn). These articles are welcome because they emphasize important concepts for clinicians. Some aspects, however, require clarification. Here we examine these articles and separate...

متن کامل

Cardiac enzyme in emergency medicine

Objective: Acute chest pain is an important and frequently occurring symptom in patients. Chest pain is often a sign of ischemic heart disease. Chest pain due to suspected Acute Coronary Syndrome (ACS) is responsible for a large and ijncreasing number of hospital attendances and admissions. Current practice for suspected ACS involves troponin testing 10–12 hours after symptom o...

متن کامل

The most sensitive double-marker method of cardiac isoenzymes of creatinine kinase, troponin I, and myoglobin in different time periods for diagnosing acute myocardial infarction

  Purpose: Myocardial infarction is among the most common diagnoses in patients admitted   to hospitals in western countries, and its rapid diagnosis is of utmost importance. This study   was conducted to determine the most sensitive double-marker cardiac isoenzyme of creatinine   kinase, troponin I, and myoglobin for diagnosing acute myocardial infarction.   Materials and Methods: This was an ...

متن کامل

Stressing the Utility of High-Sensitivity Cardiac Troponin Testing in Patients with Possible Cardiac Ischemia

Strategies to rule out myocardial infarction (MI)2 in the emergency department include stress test echocardiography, electrocardiography, and assessment of cardiac biomarkers such as troponin I and T (1). The potential for new high-sensitivity cardiac troponin testing to simplify and expedite these rule-out protocols is of great interest. Is all the hype justified? Or are we placing unreasonabl...

متن کامل

The state of cardiac troponin assays: looking bright and moving in the right direction.

Cardiac troponin assays have evolved substantially over 20 years, owing to the efforts of manufacturers to make them more precise and sensitive. These enhancements have led to high-sensitivity cardiac troponin assays, which ideally would give measureable values above the limit of detection (LoD) for 100% of healthy individuals and demonstrate an imprecision (CV) of 10% at the 99th percentile. C...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Clinical chemistry

دوره 56 7  شماره 

صفحات  -

تاریخ انتشار 2010